Title |
Depression and the Link with Cardiovascular Disease
|
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Published in |
Frontiers in Psychiatry, March 2016
|
DOI | 10.3389/fpsyt.2016.00033 |
Pubmed ID | |
Authors |
Arup K. Dhar, David A. Barton |
Abstract |
This review provides an outline of the association between major depressive disorder (MDD) and coronary heart disease (CHD). Much is known about the two individual clinical conditions; however, it is not until recently, biological mechanisms have been uncovered that link both MDD and CHD. The activation of stress pathways have been implicated as a neurochemical mechanism that links MDD and CHD. Depression is known to be associated with poorer outcomes of CHD. Psychological factors, such as major depression and stress, are now known as risk factors for developing CHD, which is as important and is independent of classic risk factors, such as hypertension, diabetes mellitus, and cigarette smoking. Both conditions have great socioeconomic importance given that depression and CHD are likely to be two of the three leading causes of global burden of disease. Better understanding of the common causal pathways will help us delineate more appropriate treatments. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | 33% |
Canada | 1 | 17% |
United States | 1 | 17% |
Switzerland | 1 | 17% |
Unknown | 1 | 17% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 6 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
India | 1 | <1% |
Canada | 1 | <1% |
Unknown | 450 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 59 | 13% |
Student > Bachelor | 57 | 13% |
Researcher | 47 | 10% |
Student > Ph. D. Student | 43 | 10% |
Student > Doctoral Student | 24 | 5% |
Other | 74 | 16% |
Unknown | 148 | 33% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 112 | 25% |
Nursing and Health Professions | 40 | 9% |
Psychology | 40 | 9% |
Biochemistry, Genetics and Molecular Biology | 21 | 5% |
Neuroscience | 19 | 4% |
Other | 54 | 12% |
Unknown | 166 | 37% |