@david_kochman "CSF:serum ratios were 0.04 - 0.08 % at 24 h after the final dose (Table 5)". But it still removes Abeta: https://t.co/CQVT0AhGYW
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4,576 followers
@JasonSynaptic @Shawn__Ferguson @AdrianoAguzzi @ZivGanOr HA. These can barely go to the brain. Look at the data that we have (most unpublished). CSF:plasma is .04% for BAN2401 (but it still removes Abeta thats true!): https://t.co/CQVT0AhGYW
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Here's the CSF:serum ratio for BAN2401 that everyone is getting all excited about...0.04% (no effect on #Alzheimers CSF biomarkers BTW): https://t.co/r1aDdn4MCH https://t.co/PVA0d4YLeh
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Safety and tolerability of BAN2401: a clinical study in Alzheimer's disease with protofibril selective Aβ antibody. https://t.co/UFijoqzYRF