13a) The other major class of drugs currently being eval'd in #IgAN is the #complement inhibitors. ✔️out 🔓https://t.co/DTG9jErlZd. At #KidneyWk we saw 1st data for the C5 inhibitor #Ravulizumabin IgAN, a drug we know well in atypical #HUS & #PNH: 🔓 htt
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RT @caioqualunque: The Emerging Role of Complement Proteins as a Target for Therapy of IgA Nephropathy | #IgAN #GlomPearls https://t.co/T2…
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48) ... (APL-2/pegcetacoplan [https://t.co/TbmbqrkVUb], ravulizumab [https://t.co/rqfOFQFh7M] & cemdisiran [https://t.co/2lM8c77bcR]) of complement activation are currently being investigated in #IgAN (see 🔓https://t.co/DTG9jErlZd). https://t.co/Ry9pEX
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9) Additional clinicopathological factors reported to ⬆️risk of progressive kidney function⬇️in #IgAN include⬆️BMI #smoking & extent of complement activation in the kidney biopsy https://t.co/B3wiujAhD5, https://t.co/ob1capLUEC, https://t.co/6T9qMZjdyh