https://t.co/vlYcshZbUW "TIGAR knockdown led to increased ROS production, elevated mitochondrial ATP production, and phosphorus oxygen ratios." "The prognosis of high TIGAR expression patients was significantly poorer than those with low TIGAR expression
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3,867 followers
https://t.co/vlYcshZbUW "TIGAR protected cancer cells from oxidative stress-caused damages, but also glycolysis defects." "TIGAR also increased the production of NADPH in gastric cancer cells."
3,867 followers
https://t.co/vlYcshZbUW "TIGAR was up-regulated compared with corresponding non-cancerous tissues in primary GCs." "TIGAR knockdown significantly reduced cell proliferation and increased apoptosis."
3,867 followers
https://t.co/vlYcshZbUW "TIGAR functions to inhibit glycolysis and promote antioxidative activities, which assists the generation of NADPH to maintain the levels of GSH and thus reduces intracellular ROS."