> #LongCovid & #MECFS as breakdown of allostasis If #allostasis is replaced by a state of allostatic dysfunction, then… —activities of interacting subsystems are insufficiently coordinated by the brain —reacting to compensate for ongoing miscalibr
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The Paradigm of Allostatic Orchestration ”#Allostasis: the role of the brain is to —serve as the center for anticipatory regulation —orchestrate operations across systems, & —support successful interaction with the environment” Front Hum Neurosci 201
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RT @8Eevert: @vin43075 @PessoaBrain > what is the copernican revolution that’s being referred to here? This excellent paper is at least ad…
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@j_b_kennedy An inevitable outcome of focusing efforts to understand it on only one part of the system at a time is missing the organizing principle of allostasis. Medicine is unable to observe, explain & address systemic phenomena — it has made itsel