https://t.co/Sm76Yq8hFo "However, we also identified the role of the HMGB1 protein in this LPC-induced pyroptosis of monocytes and endothelial cells."
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3,823 followers
https://t.co/Sm76Yq8hFo "These results agree with data shown by Lopez-Pastrana and colleagues, where LPC triggered pyroptosis of endothelial cells in a caspase-1-dependent manner in an ischemia model"
3,823 followers
https://t.co/Sm76Yq8hFo "In this work, we showed that LPC could induce pyroptosis in monocytes and endothelial cells owing to the increase in membrane pore formation and LDH released after treatment with high concentrations of LPC."
3,823 followers
https://t.co/Sm76Yq8hFo "and membrane pore formation, IL-1β, IL-18, HMGB1, and LDH release" "Pyroptosis has been shown to play important roles in cardiovascular diseases, such as atherosclerosis"