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Title |
Development of a Rapid and Confirmatory Method to Identify Ganoderic Acids in Ganoderma Mushrooms
|
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Published in |
Frontiers in Pharmacology, January 2012
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DOI | 10.3389/fphar.2012.00085 |
Pubmed ID | |
Authors |
Ying Qi, Lingling Zhao, Hao H. Sun |
Abstract |
To examine the composition of lanostanoids in Ganoderma lucidum, we have developed a liquid chromatography-mass spectrometry (LC-MS) method by using the ganoderic acids isolated in our laboratory as reference standards. The identity of 14 peaks in the high performance liquid chromatogram (HPLC) of G. lucidum has been confirmed. By using the HPLC retention times of these ganoderic acids and their mass fragmentation patterns established in this paper, one can use LC-MS to analyze G. lucidum without requiring the reference standards of these 14 ganoderic acids. Subsequently, only the HPLC-UV method would be needed to analyze routine samples of G. lucidum. |
Mendeley readers
The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 34 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 8 | 24% |
Student > Master | 5 | 15% |
Student > Ph. D. Student | 4 | 12% |
Student > Doctoral Student | 3 | 9% |
Student > Bachelor | 3 | 9% |
Other | 6 | 18% |
Unknown | 5 | 15% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 13 | 38% |
Biochemistry, Genetics and Molecular Biology | 3 | 9% |
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 9% |
Medicine and Dentistry | 2 | 6% |
Chemistry | 2 | 6% |
Other | 5 | 15% |
Unknown | 6 | 18% |