RT @NHLBI_LUNGDir: #NHLBI co-funded work finds a mechanism by which TGF-β1-dependent inhibition of #CFTR is mediated by LMTK2 in epithelial…
1,249 followers
2,809 followers
#NHLBI co-funded work finds a mechanism by which TGF-β1-dependent inhibition of #CFTR is mediated by LMTK2 in epithelial cells, suggesting controlling TGF-β1 signaling may improve membrane stability of CFTR after pharmacological rescue. @FrontCellDevBio ht
3,881 followers
New Research: TGF-β1 Augments the Apical Membrane Abundance of Lemur Tyrosine Kinase 2 to Inhibit CFTR-Mediated Chloride Transport in Human Bronchial Epithelia: The most common disease-causing mutation in the Cystic Fibrosis Transmembrane… https://t.co/b82