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Emerging Roles for Long Non-Coding RNAs in Cancer and Neurological Disorders

Overview of attention for article published in Frontiers in Genetics, January 2012
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1 X user
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1 peer review site

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105 Mendeley
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Title
Emerging Roles for Long Non-Coding RNAs in Cancer and Neurological Disorders
Published in
Frontiers in Genetics, January 2012
DOI 10.3389/fgene.2012.00025
Pubmed ID
Authors

Courtney N. Niland, Callie R. Merry, Ahmad M. Khalil

Abstract

The recent discovery of thousands of long non-coding (lnc)RNAs in the human genome has prompted investigation of the potential roles of these molecules in human biology and medicine. Indeed, it is now well documented that many lncRNAs are involved in key biological processes, including dosage compensation, genomic imprinting, chromatin regulation, alternative splicing of pre-mRNA, nuclear organization; and potentially many other biological processes, which are yet to be elucidated. Recently, a number of studies have also reported that lncRNAs are dysregulated in a number of human diseases, including several cancers and neurological disorders. Although many of these studies have fallen short of implicating lncRNAs as causative, they suggest potential roles that warrant further in depth investigations. In this review, we discuss the current state of knowledge regarding the roles of lncRNAs in cancer and neurological disorders, and suggest potential future directions in this rapidly emerging field.

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X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 105 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 3%
Germany 1 <1%
Italy 1 <1%
Chile 1 <1%
Spain 1 <1%
United Kingdom 1 <1%
Unknown 97 92%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 22 21%
Researcher 20 19%
Student > Master 15 14%
Professor 8 8%
Student > Doctoral Student 7 7%
Other 21 20%
Unknown 12 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 55 52%
Biochemistry, Genetics and Molecular Biology 20 19%
Medicine and Dentistry 6 6%
Unspecified 2 2%
Chemistry 2 2%
Other 6 6%
Unknown 14 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 June 2012.
All research outputs
#14,146,599
of 22,668,244 outputs
Outputs from Frontiers in Genetics
#3,884
of 11,727 outputs
Outputs of similar age
#153,417
of 244,068 outputs
Outputs of similar age from Frontiers in Genetics
#116
of 255 outputs
Altmetric has tracked 22,668,244 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,727 research outputs from this source. They receive a mean Attention Score of 3.7. This one has gotten more attention than average, scoring higher than 62% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 244,068 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 35th percentile – i.e., 35% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 255 others from the same source and published within six weeks on either side of this one. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.