Amoxicillin-induced gut microbiota perturbation ↑ acute intestinal immune regulation despite epidemiologic studies assoc early life ABX & later IBD, food allergies ↑ Escherichia/Shigella,Klebsiella+Bifidobacterium ↑ Tregs, fecal IgA, goblet cells
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amoxicillin→promotes acute intestinal immune regulation may be response to inflam signals derived from MB (eg released from dead bacteria &/or expanded/new species) transiently ↓ fecal bacteria+persistently ↓ diversity promotes gammaproteobacteria
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Short-Term Amoxicillin-Induced Perturbation of the Gut Microbiota Promotes Acute Intestinal Immune Regulation in Brown Norway Rats. https://t.co/rZlnFCwBhR
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Short-term amoxicillin-induced perturbation of the gut microbiota promotes acute intestinal immune regulation in brown no... - Graversen KB et al. - https://t.co/Xd7bGb20qA #microbiome