https://t.co/eCCx8HahNh "Versican's role in inflammation also depends on temporal and spatial considerations and it may play different roles whether it is involved early or late in disease and whether it is intact or degraded."
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3,798 followers
https://t.co/eCCx8HahNh "Fragments such as versikine can act as DAMPs, interacting with immune and non-immune cells stimulating pro- and anti-inflammatory cytokine release and a modified immune response in both human and murine models"
3,798 followers
https://t.co/eCCx8HahNh "The CS isolated from versican interacts with inflammatory cytokines and impacts cytokine activity"
3,798 followers
https://t.co/eCCx8HahNh "Growth factors that increase during inflammation such as platelet-derived growth factor (PDGF) & transforming growth factor-beta (TGFβ) increase CS chains length and alter CS composition, impacting the ability of versican to in