Prediction of developmental chemical toxicity based on gene networks of human embryonic stem cells

Overview of attention for article published in Nucleic Acids Research, May 2016

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https://t.co/Q2TXrwPLAn hES細胞に薬剤を処理し、DEGsのうち10個程度の遺伝子の発現変化量からSVMと遺伝子ネットワークとを組み合わせて薬剤の毒性を予測したという論文。適切に重み付けし、機械学習を行うことで予測制度が上がるようだ。選択した10遺伝子とMOAに関連性があるのか不明。

30 Nov 2019

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https://t.co/1GTekoJxmT 因みに先の毒性予測の論文はこちら（オープンアクセス）

11 Jun 2016

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Prediction of developmental chemical toxicity based on gene networks of human embryonic stem cells https://t.co/5ew1Yaut6h

10 Jun 2016

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Prediction of developmental chemical toxicity based on gene networks of human embryonic stem cells. - PubMed - NCBI https://t.co/APJ2hhN4Sd

24 May 2016

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