The Senolytic Drug Navitoclax (ABT-263) Causes Trabecular Bone Loss and Impaired Osteoprogenitor Function in Aged Mice

RT @Blagosklonny: Senolytics (drugs that kill senescent cells) are anti-cancer drugs. This is a form of cytotoxic chemotherapy. All senolyt…

[ 📝#Senolytics r not ready 4 prime time But, We r close, if current unabated Progress persists; benefiting healthy Lifespan 🧠Storm: If We could alter all Human #Germline cells to a permanent near #StemCell purity, hundreds of yrs could be added to the he

Senolytics (drugs that kill senescent cells) are anti-cancer drugs. This is a form of cytotoxic chemotherapy. All senolytics were initially developed as anti-cancer drugs. Not surprisingly they have cytotoxic side effects https://t.co/cDliyVulxt

Interesting. We can easily find the miriad benefits of #senolytics, but certainly we forget that there are toxicity caveats and that #senescent cells might not be bad in every tissue. We need more targeted therapies and better senolytics #Navitoclax #BCL2