RT @Jikkyleaks: Reference for mutations affecting the furin cleavage site early on - published July 2020. Submitted 15th June 2020. https:…
RT @Jikkyleaks: Reference for mutations affecting the furin cleavage site early on - published July 2020. Submitted 15th June 2020. https:…
RT @Jikkyleaks: Reference for mutations affecting the furin cleavage site early on - published July 2020. Submitted 15th June 2020. https:…
RT @Jikkyleaks: Reference for mutations affecting the furin cleavage site early on - published July 2020. Submitted 15th June 2020. https:…
RT @Jikkyleaks: Reference for mutations affecting the furin cleavage site early on - published July 2020. Submitted 15th June 2020. https:…
RT @Jikkyleaks: Reference for mutations affecting the furin cleavage site early on - published July 2020. Submitted 15th June 2020. https:…
RT @Jikkyleaks: Reference for mutations affecting the furin cleavage site early on - published July 2020. Submitted 15th June 2020. https:…
RT @Jikkyleaks: Reference for mutations affecting the furin cleavage site early on - published July 2020. Submitted 15th June 2020. https:…
RT @Jikkyleaks: Reference for mutations affecting the furin cleavage site early on - published July 2020. Submitted 15th June 2020. https:…
RT @Jikkyleaks: Reference for mutations affecting the furin cleavage site early on - published July 2020. Submitted 15th June 2020. https:…
RT @Jikkyleaks: Reference for mutations affecting the furin cleavage site early on - published July 2020. Submitted 15th June 2020. https:…
RT @Jikkyleaks: Reference for mutations affecting the furin cleavage site early on - published July 2020. Submitted 15th June 2020. https:…
RT @Jikkyleaks: Reference for mutations affecting the furin cleavage site early on - published July 2020. Submitted 15th June 2020. https:…
RT @Jikkyleaks: Reference for mutations affecting the furin cleavage site early on - published July 2020. Submitted 15th June 2020. https:…
RT @Jikkyleaks: Reference for mutations affecting the furin cleavage site early on - published July 2020. Submitted 15th June 2020. https:…
RT @Jikkyleaks: Reference for mutations affecting the furin cleavage site early on - published July 2020. Submitted 15th June 2020. https:…
RT @Jikkyleaks: Reference for mutations affecting the furin cleavage site early on - published July 2020. Submitted 15th June 2020. https:…
RT @Jikkyleaks: Reference for mutations affecting the furin cleavage site early on - published July 2020. Submitted 15th June 2020. https:…
RT @Jikkyleaks: Reference for mutations affecting the furin cleavage site early on - published July 2020. Submitted 15th June 2020. https:…
RT @Jikkyleaks: Reference for mutations affecting the furin cleavage site early on - published July 2020. Submitted 15th June 2020. https:…
RT @Jikkyleaks: Reference for mutations affecting the furin cleavage site early on - published July 2020. Submitted 15th June 2020. https:…
RT @Jikkyleaks: Reference for mutations affecting the furin cleavage site early on - published July 2020. Submitted 15th June 2020. https:…
RT @Jikkyleaks: Reference for mutations affecting the furin cleavage site early on - published July 2020. Submitted 15th June 2020. https:…
RT @Jikkyleaks: Reference for mutations affecting the furin cleavage site early on - published July 2020. Submitted 15th June 2020. https:…
RT @Jikkyleaks: Reference for mutations affecting the furin cleavage site early on - published July 2020. Submitted 15th June 2020. https:…
Reference for mutations affecting the furin cleavage site early on - published July 2020. Submitted 15th June 2020. https://t.co/lJja3SWL5u
@pkeetsbird @mbalter There are many furin sequences that have been patented some even 2004 and at least 23 polymorphisms in Corona virus and the Moderna one isn't unique in nature https://t.co/XbLNhN0LlG https://t.co/tDcDxvCzd2 https://t.co/NmT1VuAl67
@breakfast_dogs Maybe, but it can spread among humans without it: https://t.co/opfCoDgS2B
@Rossana38510044 @EWoodhouse7 @trvrb It baffles me why no one has identified traces of the SARS2 precursor in the 2019 GISAID samples. My guess is that the precursor didn't have the FCS. Samples in GISAID from 2020 of SARS2 with non-working FCS are evide
RT @FrontGenetics: New Research: Natural Polymorphisms Are Present in the Furin Cleavage Site of the SARS-CoV-2 Spike Glycoprotein: The fur…
RT @LDjaparidze: @MartinaSisters Hi Martina, point 10 might be arguable: Similar bat virus without FCS infecting human cells: https://t.c…
@MartinaSisters Hi Martina, point 10 might be arguable: Similar bat virus without FCS infecting human cells: https://t.co/IShIcQgfz3 SC2 samples in humans without a working FCS: https://t.co/zzR9PeSMRq SC2 minus FCS could spread among humans (of cours
@tony_vandongen @InvestingMerc @mbalter @Biorealism Tony, as of June 2020, there were human SARS2 sequences in the GISAID database with impaired/disabled FCS: https://t.co/RdijzW5HpX
And study reporting "From 45828 SARS-CoV-2 genome sequences available in the GISAID database as of June 13, 2020, 103 strains... carried various DNA mutations..." that "disabling furin-type cleavages" "completely abrogated the furin cleavage site" ht
RT @Rossana38510044: 28/ It is not possible to exclude that the original sequence coding for the FCS was designed to be inactive, but it mu…
RT @Rossana38510044: 28/ It is not possible to exclude that the original sequence coding for the FCS was designed to be inactive, but it mu…
@Parsifaler Furin, secretion pathway, extracellular TGFbeta initiates cascade? https://t.co/WMC42XzwxJ https://t.co/IhHK21UgyC https://t.co/ckNcZTfl7c https://t.co/c3crOVLPdU https://t.co/4xStvgMpab https://t.co/zI1CST88Lb https://t.co/FRoRlpMs9y https://t
RT @Rossana38510044: 28/ It is not possible to exclude that the original sequence coding for the FCS was designed to be inactive, but it mu…
RT @Rossana38510044: 28/ It is not possible to exclude that the original sequence coding for the FCS was designed to be inactive, but it mu…
RT @Rossana38510044: 28/ It is not possible to exclude that the original sequence coding for the FCS was designed to be inactive, but it mu…
RT @Rossana38510044: 28/ It is not possible to exclude that the original sequence coding for the FCS was designed to be inactive, but it mu…
“…our results revealed the furin cleavage site may not be required for SARS-CoV-2 to enter human cells in vivo…agrees w/in vitro experimental results showing that SARS-CoV-2, w/deletion of the furin cleavage site, could still enter cell lines of humans” ht
@rjohnston4 There are lots of examples of furin cleavage sites. The argument has to rest on codon usage I think, which is a little tenuous. One example from literature: https://t.co/4cUfVLnl80
Background: many coronavirus variants have furin cleavage sites (a well-known manipulation), but SARS-CoV-2 seems to have somewhat less common codon usage. How common? Some nerd, do a sequence alignment and tell me! https://t.co/4cUfVLnl80
RT @Rossana38510044: 28/ It is not possible to exclude that the original sequence coding for the FCS was designed to be inactive, but it mu…
RT @Rossana38510044: 28/ It is not possible to exclude that the original sequence coding for the FCS was designed to be inactive, but it mu…
RT @AlvaroM_ENG: Y de "obsequio" dejo este por aquí para aquellos ávidos de la lectura...😉 Polimorfismos naturales presentes en el sitio de…
RT @AlvaroM_ENG: Y de "obsequio" dejo este por aquí para aquellos ávidos de la lectura...😉 Polimorfismos naturales presentes en el sitio de…
RT @AlvaroM_ENG: Y de "obsequio" dejo este por aquí para aquellos ávidos de la lectura...😉 Polimorfismos naturales presentes en el sitio de…
Y de "obsequio" dejo este por aquí para aquellos ávidos de la lectura...😉 Polimorfismos naturales presentes en el sitio de escisión de la furina de la proteína S del #SARSCoV2 https://t.co/664bhVkYZA https://t.co/mTUZ8XoOyC
RT @Rossana38510044: 28/ It is not possible to exclude that the original sequence coding for the FCS was designed to be inactive, but it mu…
@fitterhappierAJ @MLevitt_NP2013 @Cescoxonta @andreascaie SARS-CoV-2 is not dependent on the furin cleavage site, and there have been many mutations of it & 1 deletion in Asia "our observed mutants may represent a new subgroup of SARS-CoV-2 coronavirus
RT @Rossana38510044: 28/ It is not possible to exclude that the original sequence coding for the FCS was designed to be inactive, but it mu…
28/ It is not possible to exclude that the original sequence coding for the FCS was designed to be inactive, but it mutated during human to human transmission. https://t.co/hSu0MeY33g
https://t.co/qDBQ5EpXf0 "If tropism and transmissibility of those mutant strains (in FCS) were indeed reduced, they might serve as potential live-attenuated vaccine candidates"
RT @Alzhacker: COVID-19患者から特定された変異株は、SARS-CoV2ウイルスが細胞に侵入するためのフーリン切断部位を必要としない可能性がある。 フリン切断部位が削除されたSARS-CoV-2は、依然としてヒト、アフリカミドリザル、ベイハムスターの細胞株に…
RT @zzz_as_zzz: フリン開削点が無くなって居たり、変異してフリンでは切断されない株が・・・ S1/S2とS2'の両方がTMSPSS2/Trypsinで切断されるSarscov(旧型)と同じ構造に戻るので、振る舞いもある程度同じになる? この部分はヘパリンなどの…
RT @Alzhacker: COVID-19患者から特定された変異株は、SARS-CoV2ウイルスが細胞に侵入するためのフーリン切断部位を必要としない可能性がある。 フリン切断部位が削除されたSARS-CoV-2は、依然としてヒト、アフリカミドリザル、ベイハムスターの細胞株に…
フリン開削点が無くなって居たり、変異してフリンでは切断されない株が・・・ S1/S2とS2'の両方がTMSPSS2/Trypsinで切断されるSarscov(旧型)と同じ構造に戻るので、振る舞いもある程度同じになる? この部分はヘパリンなどのGAGに良くくっ付く部分でもあるので、ヘパリンの効能も減るのかも。 https://t.co/EiLMkGLnAJ
COVID-19患者から特定された変異株は、SARS-CoV2ウイルスが細胞に侵入するためのフーリン切断部位を必要としない可能性がある。 フリン切断部位が削除されたSARS-CoV-2は、依然としてヒト、アフリカミドリザル、ベイハムスターの細胞株に侵入する可能性がある。 https://t.co/8UgcWyYSw8
RT @FrontGenetics: New Research: Natural Polymorphisms Are Present in the Furin Cleavage Site of the SARS-CoV-2 Spike Glycoprotein: The fur…
New Research: Natural Polymorphisms Are Present in the Furin Cleavage Site of the SARS-CoV-2 Spike Glycoprotein: The furin cleavage site in the spike glycoprotein of the SARS-CoV-2 coronavirus is considered important for the virus to enter the… https://t.c
@Rossana38510044 ( lo vi en E.D, y viene del Seeker ) el misterio se hace aun mas imenso para mi !!!! " Our results revealed that the furin cleavage site might not be required for SARS-CoV-2 to enter human cells in vivo". https://t.co/W4feGSIq99
RT @TheSeeker268: Natural Polymorphisms Are Present in the Furin Cleavage Site of the SARS-CoV-2 Spike Glycoprotein https://t.co/zwXVspVYO1
RT @TheSeeker268: Natural Polymorphisms Are Present in the Furin Cleavage Site of the SARS-CoV-2 Spike Glycoprotein https://t.co/zwXVspVYO1
RT @TheSeeker268: Natural Polymorphisms Are Present in the Furin Cleavage Site of the SARS-CoV-2 Spike Glycoprotein https://t.co/zwXVspVYO1
RT @TheSeeker268: Natural Polymorphisms Are Present in the Furin Cleavage Site of the SARS-CoV-2 Spike Glycoprotein https://t.co/zwXVspVYO1
RT @TheSeeker268: Natural Polymorphisms Are Present in the Furin Cleavage Site of the SARS-CoV-2 Spike Glycoprotein https://t.co/zwXVspVYO1
"By analyzing 45828 SARS-CoV-2 genome sequences, we identified 103 strains of SARS-CoV-2 with various DNA mutations including 18 unique non-synonymous point mutations, one deletion, and six gains of premature stop codon that may affect the furin cleavage s
Natural Polymorphisms Are Present in the Furin Cleavage Site of the SARS-CoV-2 Spike Glycoprotein https://t.co/zwXVspVYO1