FYI - autophagy... https://t.co/UXJs89aPoo
RT @GanineVanalst: @alexandrosM @carlososuna86 @scotub @Wezuwezu @t_ayorinde Purely speculative, but since it's known to bioaccumulate in l…
@alexandrosM @JoomiKim1 Good overview. I like the question: "Why aren’t we talking about ivermectin in fat tissue? I'd like to see that angle explored as well. Not just adipose tissue, but I've had lipid rafts stuck in my head since reading this last ye
RT @Niatonin: SARS-CoV-2, similar to MERS-CoV, strongly reduced the autophagic flux in infected cell lines downregulating the AMPK/mTORC1 p…
@alexandrosM @carlososuna86 @scotub @Wezuwezu @t_ayorinde Purely speculative, but since it's known to bioaccumulate in lipids, I wondered whether a possible mechanism of action involved it bioaccumulating in lipid rafts & exerting its antiviral propert
@ydeigin @alexandrosM @BretWeinstein @HeatherEHeying Purely speculative, but if it bioaccumulates in fat/lipids perhaps this is one potential mechanism of action. Could it accumulate in lipid rafts blocking replication there? https://t.co/ed1usJzZOL
RT @NiacinIsHealth: SARS-CoV-2, similar to MERS-CoV, strongly reduced the autophagic flux in infected cell lines downregulating the AMPK/mT…
@gkierzek ref. https://t.co/gsWjj4am8V Si le SARS-Cov-2 ne peut s'accrocher au «RAFTS» des cellules-cible protégées par le glycocalyx endothèlial ou si celui-ci est «abîmé», protégées par HBPM, alors virus n'est qu'une «pierre qui roule» jusqu'à sa neutra
@__ice9 @Acute_Pulmo_Med @jasonsknight @farid__jalali @drakchaurasia @dronico @DrLuana_ID @RIGHT_COVID19 @f_g_zampieri @VirusesImmunity Caveola and coronavirus endocytosis https://t.co/73Zlhb7BWy https://t.co/FfZPcj65rb
RT @Alzhacker: https://t.co/LnMKfsZEM3 脂質ラフトおよびオートファジーとのコロナウイルスの相互作用が有望な治療標的を明らかにする ウイルスは脂質ラフトを利用して標的細胞の感染を獲得する。したがって脂質ラフトの薬理学的枯渇または破壊は、ウイ…
https://t.co/LnMKfsZEM3 脂質ラフトおよびオートファジーとのコロナウイルスの相互作用が有望な治療標的を明らかにする ウイルスは脂質ラフトを利用して標的細胞の感染を獲得する。したがって脂質ラフトの薬理学的枯渇または破壊は、ウイルス複製を低減、阻害するためのツールを提供する可能性がある
New Research: Coronavirus Interplay With Lipid Rafts and Autophagy Unveils Promising Therapeutic Targets https://t.co/dLjB5IPCXH #microbiology