A Small Molecule Inhibitor of CTP Synthetase Identified by Differential Activity on a Bacillus subtilis Mutant Deficient in Class A Penicillin-Binding Proteins https://t.co/N8pVNtBqE2
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Wonder if this CTP synthase inhibitor would have effect on whatever people define as condensates. Would also be interesting to look at them in the mutant cancer cell line referenced in that 1985 paper linked above. https://t.co/OphtSruPuf
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Little gem in here They were trying to find RodA inhibitor by screening for compounds that knocked down growth of mutant lacking known class A PBPs > wt What did they hit instead of RodA? CTP synthase! https://t.co/3u5vpRQ6pV
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A Small Molecule Inhibitor of CTP Synthetase Identified by Differential Activity on a Bacillus subtilis Mutant Deficient in Class A Penicillin-Binding Proteins. https://t.co/lmOuGsRFnH