Title |
Emerging Roles of Eosinophils and Eosinophil-Derived Lipid Mediators in the Resolution of Inflammation
|
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Published in |
Frontiers in immunology, January 2012
|
DOI | 10.3389/fimmu.2012.00270 |
Pubmed ID | |
Authors |
Yosuke Isobe, Taiga Kato, Makoto Arita |
Abstract |
Acute inflammation and its resolution are essential processes for tissue protection and homeostasis. Once thought to be a passive process, the resolution of inflammation is now shown to involve active biochemical programs that enable inflamed tissues to return to homeostasis. The mechanisms by which acute inflammation is resolved are of interest, and research in recent years has uncovered new endogenous anti-inflammatory and pro-resolving lipid mediators (i.e., lipoxins, resolvins, protectin, and maresin) generated from polyunsaturated fatty acids (PUFAs). This review presents new insights into the cellular and molecular mechanisms of inflammatory resolution, especially the roles of eosinophils, and a series of omega-3 PUFA-derived anti-inflammatory lipid mediators that they generate. |
X Demographics
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Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 115 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 21 | 18% |
Student > Ph. D. Student | 17 | 15% |
Student > Master | 17 | 15% |
Student > Bachelor | 13 | 11% |
Student > Doctoral Student | 11 | 10% |
Other | 15 | 13% |
Unknown | 21 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 23 | 20% |
Agricultural and Biological Sciences | 23 | 20% |
Biochemistry, Genetics and Molecular Biology | 15 | 13% |
Immunology and Microbiology | 15 | 13% |
Pharmacology, Toxicology and Pharmaceutical Science | 5 | 4% |
Other | 10 | 9% |
Unknown | 24 | 21% |