@nature Related: mtDNA removal (and, by extension, mtRNA removal) affects nuclear gene expression in mouse breast cancer cell lines. We also found immune changes, but it doesn't seem to be generalisable to other types of tumours. https://t.co/mTbeidBREb
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Mitochondrial DNA Affects the Expression of Nuclear Genes Involved in Immune and Stress Responses in a Breast Cancer Model https://t.co/stAItiNkYK https://t.co/FQlrzvqwVK
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For those who don't have their own long-read cDNA data, we've got a published dataset from mouse 4T1 breast cancer cell lines, see the 'Data Availability' section of this paper: https://t.co/mTbeidBREb
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RT @FrontPhysiol: New Research: Mitochondrial DNA Affects the Expression of Nuclear Genes Involved in Immune and Stress Responses in a Brea…