“Next, we introduce several types of common epileptic diseases, including the glucose transporter (GLUT1) deficiency syndrome, hypoglycemia, creatine deficits, and mitochondrial encephalomyopathies.” https://t.co/vRNGd30xQg
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310 followers
“Lactate originating from the astrocytes is again catalyzed to pyruvate by lactate dehydrogenase, and the pyruvate could be carried into the mitochondria and be utilized as an energy metabolite in the Krebs cycle (Figure 1).” https://t.co/vRNGd30xQg
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“…in the brain, lactate produced in astrocytes fuels the mitochondrial tricarboxylic acid (TCA) cycle of neurons in a proprietary way, i.e., the ANLS (28).” https://t.co/vRNGd30xQg
310 followers
“This evidence showed that decreased glycolysis due to insufficient glucose concentration impairs neuronal function, and glycolysis is crucial for sustaining synaptic function.” https://t.co/vRNGd30xQg