Specific enzymes, named sheddases, as well as metalloproteinases (MMPs), heparanase, and hyaluronidase degrade #glycocalyx. Sheddases are activated by pro-inflammatory cytokines such as TNFα, IL-1beta, IL-6, IL-8 and also by shear stress, hypoxia, and ROS.
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RT @FrontPhysiol: New Research: The Role of Glycocalyx and Caveolae in Vascular Homeostasis and Diseases https://t.co/USicZrsson #Physiology
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New Research: The Role of Glycocalyx and Caveolae in Vascular Homeostasis and Diseases https://t.co/USicZrsson #Physiology
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