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Rugged Large Volume Injection for Sensitive Capillary LC-MS Environmental Monitoring

Overview of attention for article published in Frontiers in Chemistry, August 2017
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Title
Rugged Large Volume Injection for Sensitive Capillary LC-MS Environmental Monitoring
Published in
Frontiers in Chemistry, August 2017
DOI 10.3389/fchem.2017.00062
Pubmed ID
Authors

Hanne Roberg-Larsen, Silvija Abele, Deniz Demir, Diana Dzabijeva, Sunniva F. Amundsen, Steven R. Wilson, Vadims Bartkevics, Elsa Lundanes

Abstract

A rugged and high throughput capillary column (cLC) LC-MS switching platform using large volume injection and on-line automatic filtration and filter back-flush (AFFL) solid phase extraction (SPE) for analysis of environmental water samples with minimal sample preparation is presented. Although narrow columns and on-line sample preparation are used in the platform, high ruggedness is achieved e.g., injection of 100 non-filtrated water samples did not result in a pressure rise/clogging of the SPE/capillary columns (inner diameter 300 μm). In addition, satisfactory retention time stability and chromatographic resolution were also features of the system. The potential of the platform for environmental water samples was demonstrated with various pharmaceutical products, which had detection limits (LOD) in the 0.05-12.5 ng/L range. Between-day and within-day repeatability of selected analytes were <20% RSD.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 11 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 11 100%

Demographic breakdown

Readers by professional status Count As %
Professor > Associate Professor 2 18%
Student > Ph. D. Student 2 18%
Lecturer 1 9%
Student > Bachelor 1 9%
Student > Master 1 9%
Other 1 9%
Unknown 3 27%
Readers by discipline Count As %
Chemistry 6 55%
Agricultural and Biological Sciences 1 9%
Pharmacology, Toxicology and Pharmaceutical Science 1 9%
Unknown 3 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 September 2017.
All research outputs
#20,444,703
of 22,999,744 outputs
Outputs from Frontiers in Chemistry
#2,934
of 6,008 outputs
Outputs of similar age
#276,281
of 316,382 outputs
Outputs of similar age from Frontiers in Chemistry
#13
of 24 outputs
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