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CRISPR/Cascade 9-Mediated Genome Editing-Challenges and Opportunities

Overview of attention for article published in Frontiers in Genetics, July 2018
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  • Good Attention Score compared to outputs of the same age (70th percentile)
  • Good Attention Score compared to outputs of the same age and source (77th percentile)

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108 Mendeley
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Title
CRISPR/Cascade 9-Mediated Genome Editing-Challenges and Opportunities
Published in
Frontiers in Genetics, July 2018
DOI 10.3389/fgene.2018.00240
Pubmed ID
Authors

Bhaskar Roy, Jing Zhao, Chao Yang, Wen Luo, Teng Xiong, Yong Li, Xiaodong Fang, Guanjun Gao, Chabungbam O. Singh, Lise Madsen, Yong Zhou, Karsten Kristiansen

Abstract

Clustered Regularly Interspaced Palindromic Repeats (CRISPR) and Cascade 9 (also known as Cas9, CRISPR associated protein 9) confer protection against invading viruses or plasmids. The CRISPR/Cascade 9 system constitutes one of the most powerful genome technologies available to researchers today. So far, this technology has enabled efficient genome editing and modification in several model organisms and has successfully been used in biomedicine and biomedical engineering. However, challenges for efficient and safe genetic manipulation in several organisms persist. Here, we review functional approaches and future challenges associated with the use of the CRISPR/Cascade 9 genome editing system and discuss opportunities, ethical issues and future directions within this field.

X Demographics

X Demographics

The data shown below were collected from the profiles of 11 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 108 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 108 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 21 19%
Student > Ph. D. Student 15 14%
Researcher 14 13%
Student > Master 12 11%
Professor 6 6%
Other 13 12%
Unknown 27 25%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 36 33%
Agricultural and Biological Sciences 20 19%
Medicine and Dentistry 6 6%
Social Sciences 3 3%
Computer Science 2 2%
Other 11 10%
Unknown 30 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 August 2018.
All research outputs
#6,600,809
of 26,216,692 outputs
Outputs from Frontiers in Genetics
#1,854
of 13,877 outputs
Outputs of similar age
#102,603
of 343,873 outputs
Outputs of similar age from Frontiers in Genetics
#31
of 140 outputs
Altmetric has tracked 26,216,692 research outputs across all sources so far. This one has received more attention than most of these and is in the 74th percentile.
So far Altmetric has tracked 13,877 research outputs from this source. They receive a mean Attention Score of 3.9. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 343,873 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 140 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.