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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Cross-Presentation of Cell-Associated Antigens by MHC Class I in Dendritic Cell Subsets
|
|---|---|
| Published in |
Frontiers in immunology, January 2015
|
| DOI | 10.3389/fimmu.2015.00363 |
| Pubmed ID | |
| Authors |
Enric Gutiérrez-Martínez, Remi Planès, Giorgio Anselmi, Matthew Reynolds, Shinelle Menezes, Aimé Cézaire Adiko, Loredana Saveanu, Pierre Guermonprez |
| Abstract |
Dendritic cells (DCs) have the unique ability to pick up dead cells carrying antigens in tissue and migrate to the lymph nodes where they can cross-present cell-associated antigens by MHC class I to CD8(+) T cells. There is strong in vivo evidence that the mouse XCR1(+) DCs subset acts as a key player in this process. The intracellular processes underlying cross-presentation remain controversial and several pathways have been proposed. Indeed, a wide number of studies have addressed the cellular process of cross-presentation in vitro using a variety of sources of antigen and antigen-presenting cells. Here, we review the in vivo and in vitro evidence supporting the current mechanistic models and disscuss their physiological relevance to the cross-presentation of cell-associated antigens by DCs subsets. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Portugal | 1 | 33% |
| United Kingdom | 1 | 33% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Science communicators (journalists, bloggers, editors) | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 338 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 1 | <1% |
| France | 1 | <1% |
| Brazil | 1 | <1% |
| United Kingdom | 1 | <1% |
| Mexico | 1 | <1% |
| Unknown | 333 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 88 | 26% |
| Student > Master | 44 | 13% |
| Researcher | 43 | 13% |
| Student > Bachelor | 39 | 12% |
| Student > Postgraduate | 17 | 5% |
| Other | 38 | 11% |
| Unknown | 69 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Immunology and Microbiology | 84 | 25% |
| Agricultural and Biological Sciences | 72 | 21% |
| Biochemistry, Genetics and Molecular Biology | 49 | 14% |
| Medicine and Dentistry | 17 | 5% |
| Pharmacology, Toxicology and Pharmaceutical Science | 12 | 4% |
| Other | 24 | 7% |
| Unknown | 80 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 January 2023.
All research outputs
#6,960,723
of 25,461,852 outputs
Outputs from Frontiers in immunology
#7,445
of 31,698 outputs
Outputs of similar age
#85,828
of 359,918 outputs
Outputs of similar age from Frontiers in immunology
#42
of 173 outputs
Altmetric has tracked 25,461,852 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 31,698 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 359,918 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 75% of its contemporaries.
We're also able to compare this research output to 173 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.