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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Interferon-Lambda: A Potent Regulator of Intestinal Viral Infections
|
|---|---|
| Published in |
Frontiers in immunology, June 2017
|
| DOI | 10.3389/fimmu.2017.00749 |
| Pubmed ID | |
| Authors |
Sanghyun Lee, Megan T. Baldridge |
| Abstract |
Interferon-lambda (IFN-λ) is a recently described cytokine found to be of critical importance in innate immune regulation of intestinal viruses. Endogenous IFN-λ has potent antiviral effects and has been shown to control multiple intestinal viruses and may represent a factor that contributes to human variability in response to infection. Importantly, recombinant IFN-λ has therapeutic potential against enteric viral infections, many of which lack other effective treatments. In this mini-review, we describe recent advances regarding IFN-λ-mediated regulation of enteric viruses with important clinical relevance including rotavirus, reovirus, and norovirus. We also briefly discuss IFN-λ interactions with other cytokines important in the intestine, and how IFN-λ may play a role in regulation of intestinal viruses by the commensal microbiome. Finally, we indicate currently outstanding questions regarding IFN-λ control of enteric infections that remain to be explored to enhance our understanding of this important immune molecule. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 1 | 14% |
| United States | 1 | 14% |
| Unknown | 5 | 71% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 6 | 86% |
| Scientists | 1 | 14% |
Mendeley readers
The data shown below were compiled from readership statistics for 117 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 117 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 23 | 20% |
| Student > Ph. D. Student | 20 | 17% |
| Student > Doctoral Student | 12 | 10% |
| Student > Master | 11 | 9% |
| Student > Bachelor | 10 | 9% |
| Other | 16 | 14% |
| Unknown | 25 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Immunology and Microbiology | 36 | 31% |
| Agricultural and Biological Sciences | 24 | 21% |
| Biochemistry, Genetics and Molecular Biology | 12 | 10% |
| Medicine and Dentistry | 7 | 6% |
| Unspecified | 2 | 2% |
| Other | 9 | 8% |
| Unknown | 27 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 January 2021.
All research outputs
#8,476,767
of 25,382,440 outputs
Outputs from Frontiers in immunology
#10,600
of 31,531 outputs
Outputs of similar age
#125,787
of 327,487 outputs
Outputs of similar age from Frontiers in immunology
#164
of 407 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one has received more attention than most of these and is in the 66th percentile.
So far Altmetric has tracked 31,531 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has gotten more attention than average, scoring higher than 65% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 327,487 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.
We're also able to compare this research output to 407 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 58% of its contemporaries.