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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The Mechanisms of Action of Ribosome-Targeting Peptide Antibiotics
|
|---|---|
| Published in |
Frontiers in Molecular Biosciences, May 2018
|
| DOI | 10.3389/fmolb.2018.00048 |
| Pubmed ID | |
| Authors |
Yury S. Polikanov, Nikolay A. Aleksashin, Bertrand Beckert, Daniel N. Wilson |
| Abstract |
The ribosome is one of the major targets in the cell for clinically used antibiotics. However, the increase in multidrug resistant bacteria is rapidly reducing the effectiveness of our current arsenal of ribosome-targeting antibiotics, highlighting the need for the discovery of compounds with new scaffolds that bind to novel sites on the ribosome. One possible avenue for the development of new antimicrobial agents is by characterization and optimization of ribosome-targeting peptide antibiotics. Biochemical and structural data on ribosome-targeting peptide antibiotics illustrates the large diversity of scaffolds, binding interactions with the ribosome as well as mechanism of action to inhibit translation. The availability of high-resolution structures of ribosomes in complex with peptide antibiotics opens the way to structure-based design of these compounds as novel antimicrobial agents. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 1 | 14% |
| France | 1 | 14% |
| Switzerland | 1 | 14% |
| Unknown | 4 | 57% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 57% |
| Scientists | 2 | 29% |
| Science communicators (journalists, bloggers, editors) | 1 | 14% |
Mendeley readers
The data shown below were compiled from readership statistics for 255 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 255 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 44 | 17% |
| Student > Master | 39 | 15% |
| Student > Bachelor | 31 | 12% |
| Researcher | 31 | 12% |
| Student > Doctoral Student | 10 | 4% |
| Other | 28 | 11% |
| Unknown | 72 | 28% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 76 | 30% |
| Agricultural and Biological Sciences | 32 | 13% |
| Chemistry | 24 | 9% |
| Immunology and Microbiology | 16 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 10 | 4% |
| Other | 21 | 8% |
| Unknown | 76 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 May 2018.
All research outputs
#6,880,398
of 23,052,509 outputs
Outputs from Frontiers in Molecular Biosciences
#609
of 3,888 outputs
Outputs of similar age
#118,141
of 326,851 outputs
Outputs of similar age from Frontiers in Molecular Biosciences
#9
of 32 outputs
Altmetric has tracked 23,052,509 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 3,888 research outputs from this source. They receive a mean Attention Score of 3.3. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 326,851 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.
We're also able to compare this research output to 32 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.