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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Diagnostic Value of microRNA for Alzheimer’s Disease: A Systematic Review and Meta-Analysis
|
|---|---|
| Published in |
Frontiers in Aging Neuroscience, February 2016
|
| DOI | 10.3389/fnagi.2016.00013 |
| Pubmed ID | |
| Authors |
Yong-Bo Hu, Chun-Bo Li, Ning Song, Yang Zou, Sheng-Di Chen, Ru-Jing Ren, Gang Wang |
| Abstract |
Sound evidence indicates that microRNAs (miRNAs) are aberrantly expressed in Alzheimer's disease (AD) patients. We performed a systematic review and meta-analysis to investigate the role of miRNA in AD pathogenesis and their clinical diagnostic value; a systematic review of literature and meta-analysis of clinical trials were performed. In the systematic review, 236 papers were included, and we reviewed the dysregulated miRNA expression in different parts of AD patients in order to identify the relationship between aberrantly expressed miRNAs and AD pathology. In the subsequent meta-analysis, seven studies were statistically analyzed with the following results: pooled sensitivity 0.86 (95%CI 0.79-0.90), pooled specificity 0.87 (95%CI 0.72-0.95), diagnostic odds ratio (28.29), and the area under the curve (0.87). In conclusion, our review indicated that aberrant expression of various miRNAs plays an important role in the pathological process of AD, and statistical analysis of quantitative studies reveal the potential value of specific miRNAs in the diagnosis of AD. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 134 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Estonia | 1 | <1% |
| Brazil | 1 | <1% |
| Unknown | 132 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 27 | 20% |
| Student > Ph. D. Student | 23 | 17% |
| Student > Master | 16 | 12% |
| Student > Bachelor | 13 | 10% |
| Student > Doctoral Student | 7 | 5% |
| Other | 23 | 17% |
| Unknown | 25 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 25 | 19% |
| Agricultural and Biological Sciences | 13 | 10% |
| Medicine and Dentistry | 13 | 10% |
| Neuroscience | 13 | 10% |
| Pharmacology, Toxicology and Pharmaceutical Science | 8 | 6% |
| Other | 27 | 20% |
| Unknown | 35 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 February 2016.
All research outputs
#3,071,216
of 22,844,985 outputs
Outputs from Frontiers in Aging Neuroscience
#1,505
of 4,792 outputs
Outputs of similar age
#57,917
of 400,364 outputs
Outputs of similar age from Frontiers in Aging Neuroscience
#28
of 77 outputs
Altmetric has tracked 22,844,985 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,792 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.0. This one has gotten more attention than average, scoring higher than 66% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 400,364 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 77 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.