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The Indispensable Roles of Microglia and Astrocytes during Brain Development

Overview of attention for article published in Frontiers in Human Neuroscience, November 2016
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (95th percentile)
  • High Attention Score compared to outputs of the same age and source (90th percentile)

Mentioned by

news
7 news outlets
policy
1 policy source
twitter
10 X users
facebook
3 Facebook pages

Citations

dimensions_citation
411 Dimensions

Readers on

mendeley
878 Mendeley
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Title
The Indispensable Roles of Microglia and Astrocytes during Brain Development
Published in
Frontiers in Human Neuroscience, November 2016
DOI 10.3389/fnhum.2016.00566
Pubmed ID
Authors

Kitty Reemst, Stephen C. Noctor, Paul J. Lucassen, Elly M. Hol

Abstract

Glia are essential for brain functioning during development and in the adult brain. Here, we discuss the various roles of both microglia and astrocytes, and their interactions during brain development. Although both cells are fundamentally different in origin and function, they often affect the same developmental processes such as neuro-/gliogenesis, angiogenesis, axonal outgrowth, synaptogenesis and synaptic pruning. Due to their important instructive roles in these processes, dysfunction of microglia or astrocytes during brain development could contribute to neurodevelopmental disorders and potentially even late-onset neuropathology. A better understanding of the origin, differentiation process and developmental functions of microglia and astrocytes will help to fully appreciate their role both in the developing as well as in the adult brain, in health and disease.

X Demographics

X Demographics

The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 878 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 1 <1%
Germany 1 <1%
Unknown 876 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 183 21%
Student > Bachelor 136 15%
Student > Master 130 15%
Researcher 94 11%
Student > Doctoral Student 45 5%
Other 84 10%
Unknown 206 23%
Readers by discipline Count As %
Neuroscience 249 28%
Agricultural and Biological Sciences 135 15%
Biochemistry, Genetics and Molecular Biology 120 14%
Medicine and Dentistry 44 5%
Immunology and Microbiology 16 2%
Other 75 9%
Unknown 239 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 64. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 December 2022.
All research outputs
#684,142
of 25,874,560 outputs
Outputs from Frontiers in Human Neuroscience
#297
of 7,769 outputs
Outputs of similar age
#12,886
of 320,743 outputs
Outputs of similar age from Frontiers in Human Neuroscience
#16
of 167 outputs
Altmetric has tracked 25,874,560 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,769 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.1. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 320,743 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 167 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.