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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The Adenosinergic Signaling: A Complex but Promising Therapeutic Target for Alzheimer’s Disease
|
|---|---|
| Published in |
Frontiers in Neuroscience, August 2018
|
| DOI | 10.3389/fnins.2018.00520 |
| Pubmed ID | |
| Authors |
Lucrezia Cellai, Kevin Carvalho, Emilie Faivre, Aude Deleau, Didier Vieau, Luc Buée, David Blum, Céline Mériaux, Victoria Gomez-Murcia |
| Abstract |
Alzheimer's disease (AD) is the most common neurodegenerative disorder in elderly people. AD is characterized by a progressive cognitive decline and it is neuropathologically defined by two hallmarks: extracellular deposits of aggregated β-amyloid (Aβ) peptides and intraneuronal fibrillar aggregates of hyper- and abnormally phosphorylated Tau proteins. AD results from multiple genetic and environmental risk factors. Epidemiological studies reported beneficial effects of caffeine, a non-selective adenosine receptors antagonist. In the present review, we discuss the impact of caffeine and of adenosinergic system modulation on AD, in terms of pathology and therapeutics. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 2 | 18% |
| Canada | 1 | 9% |
| Italy | 1 | 9% |
| Spain | 1 | 9% |
| Belgium | 1 | 9% |
| Switzerland | 1 | 9% |
| Unknown | 4 | 36% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 9 | 82% |
| Scientists | 2 | 18% |
Mendeley readers
The data shown below were compiled from readership statistics for 66 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 66 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 9 | 14% |
| Student > Bachelor | 9 | 14% |
| Researcher | 8 | 12% |
| Student > Ph. D. Student | 8 | 12% |
| Other | 6 | 9% |
| Other | 9 | 14% |
| Unknown | 17 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 11 | 17% |
| Neuroscience | 10 | 15% |
| Medicine and Dentistry | 7 | 11% |
| Agricultural and Biological Sciences | 6 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 8% |
| Other | 7 | 11% |
| Unknown | 20 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 15. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 August 2018.
All research outputs
#2,414,141
of 25,385,509 outputs
Outputs from Frontiers in Neuroscience
#1,445
of 11,542 outputs
Outputs of similar age
#47,526
of 341,622 outputs
Outputs of similar age from Frontiers in Neuroscience
#44
of 231 outputs
Altmetric has tracked 25,385,509 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 11,542 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.0. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 341,622 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 231 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.