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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Biophysical Properties of Optogenetic Tools and Their Application for Vision Restoration Approaches
|
|---|---|
| Published in |
Frontiers in Systems Neuroscience, September 2016
|
| DOI | 10.3389/fnsys.2016.00074 |
| Pubmed ID | |
| Authors |
Simon D. Klapper, Anka Swiersy, Ernst Bamberg, Volker Busskamp |
| Abstract |
Optogenetics is the use of genetically encoded light-activated proteins to manipulate cells in a minimally invasive way using light. The most prominent example is channelrhodopsin-2 (ChR2), which allows the activation of electrically excitable cells via light-dependent depolarization. The combination of ChR2 with hyperpolarizing-light-driven ion pumps such as the Cl(-) pump halorhodopsin (NpHR) enables multimodal remote control of neuronal cells in culture, tissue, and living animals. Very soon, it became obvious that this method offers a chance of gene therapy for many diseases affecting vision. Here, we will give a brief introduction to retinal function and retinal diseases; optogenetic vision restoration strategies will be highlighted. We will discuss the functional and structural properties of rhodopsin-based optogenetic tools and analyze the potential for the application of vision restoration. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 33% |
| Unknown | 2 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 139 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 1 | <1% |
| Unknown | 138 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 22 | 16% |
| Researcher | 21 | 15% |
| Student > Ph. D. Student | 20 | 14% |
| Student > Bachelor | 19 | 14% |
| Student > Doctoral Student | 11 | 8% |
| Other | 19 | 14% |
| Unknown | 27 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 27 | 19% |
| Biochemistry, Genetics and Molecular Biology | 22 | 16% |
| Agricultural and Biological Sciences | 18 | 13% |
| Medicine and Dentistry | 18 | 13% |
| Engineering | 9 | 6% |
| Other | 12 | 9% |
| Unknown | 33 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 September 2023.
All research outputs
#7,457,701
of 26,550,749 outputs
Outputs from Frontiers in Systems Neuroscience
#531
of 1,413 outputs
Outputs of similar age
#104,656
of 351,798 outputs
Outputs of similar age from Frontiers in Systems Neuroscience
#6
of 21 outputs
Altmetric has tracked 26,550,749 research outputs across all sources so far. This one has received more attention than most of these and is in the 71st percentile.
So far Altmetric has tracked 1,413 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.4. This one has gotten more attention than average, scoring higher than 61% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 351,798 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 21 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.