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The Clinical Landscape of Circulating Tumor DNA in Gastrointestinal Malignancies

Overview of attention for article published in Frontiers in oncology, July 2018
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  • Above-average Attention Score compared to outputs of the same age and source (57th percentile)

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4 X users

Citations

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7 Dimensions

Readers on

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39 Mendeley
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Title
The Clinical Landscape of Circulating Tumor DNA in Gastrointestinal Malignancies
Published in
Frontiers in oncology, July 2018
DOI 10.3389/fonc.2018.00263
Pubmed ID
Authors

Kentaro Sawada, Daisuke Kotani, Hideaki Bando

Abstract

Technologies for genomic analyses have revealed more details in cancer biology and have changed standard treatments for cancer, including the introduction of targeted gene-specific therapy. Currently, liquid biopsies are increasingly being utilized in clinical trials and research settings to analyze circulating tumor DNA (ctDNA) from peripheral blood. Several studies have shown the potential of ctDNA in the screening, prognostication, molecular profiling, and monitoring of gastrointestinal malignancies. Although limitations continue to exist in the use of ctDNA, such as method standardization, the sensitivity, concordance with tumor tissue, and regulatory issues, this field offers promising benefits for cancer treatment. A deeper understanding of tumor biology via ctDNA analyses and ctDNA-guided clinical trials will lead to the increasing use of ctDNA in clinical practice in the near future; this development will result in the improvement of outcomes among patients with gastrointestinal malignancies.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 39 100%

Demographic breakdown

Readers by professional status Count As %
Other 9 23%
Student > Ph. D. Student 7 18%
Researcher 6 15%
Student > Master 4 10%
Student > Doctoral Student 2 5%
Other 1 3%
Unknown 10 26%
Readers by discipline Count As %
Medicine and Dentistry 13 33%
Biochemistry, Genetics and Molecular Biology 4 10%
Nursing and Health Professions 3 8%
Agricultural and Biological Sciences 3 8%
Economics, Econometrics and Finance 3 8%
Other 2 5%
Unknown 11 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 August 2018.
All research outputs
#15,313,795
of 25,706,302 outputs
Outputs from Frontiers in oncology
#4,517
of 22,767 outputs
Outputs of similar age
#180,455
of 340,594 outputs
Outputs of similar age from Frontiers in oncology
#64
of 153 outputs
Altmetric has tracked 25,706,302 research outputs across all sources so far. This one is in the 40th percentile – i.e., 40% of other outputs scored the same or lower than it.
So far Altmetric has tracked 22,767 research outputs from this source. They receive a mean Attention Score of 3.1. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 340,594 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 153 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 57% of its contemporaries.