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Development of a Rapid and Confirmatory Method to Identify Ganoderic Acids in Ganoderma Mushrooms

Overview of attention for article published in Frontiers in Pharmacology, January 2012
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Title
Development of a Rapid and Confirmatory Method to Identify Ganoderic Acids in Ganoderma Mushrooms
Published in
Frontiers in Pharmacology, January 2012
DOI 10.3389/fphar.2012.00085
Pubmed ID
Authors

Ying Qi, Lingling Zhao, Hao H. Sun

Abstract

To examine the composition of lanostanoids in Ganoderma lucidum, we have developed a liquid chromatography-mass spectrometry (LC-MS) method by using the ganoderic acids isolated in our laboratory as reference standards. The identity of 14 peaks in the high performance liquid chromatogram (HPLC) of G. lucidum has been confirmed. By using the HPLC retention times of these ganoderic acids and their mass fragmentation patterns established in this paper, one can use LC-MS to analyze G. lucidum without requiring the reference standards of these 14 ganoderic acids. Subsequently, only the HPLC-UV method would be needed to analyze routine samples of G. lucidum.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 33 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 33 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 24%
Student > Master 5 15%
Student > Ph. D. Student 4 12%
Student > Doctoral Student 3 9%
Student > Bachelor 3 9%
Other 7 21%
Unknown 3 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 14 42%
Biochemistry, Genetics and Molecular Biology 3 9%
Pharmacology, Toxicology and Pharmaceutical Science 3 9%
Medicine and Dentistry 2 6%
Chemistry 2 6%
Other 6 18%
Unknown 3 9%