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X Demographics
Mendeley readers
Attention Score in Context
| Title |
A New Personalized Cooling Protocol to Activate Brown Adipose Tissue in Young Adults
|
|---|---|
| Published in |
Frontiers in Physiology, November 2017
|
| DOI | 10.3389/fphys.2017.00863 |
| Pubmed ID | |
| Authors |
Borja Martinez-Tellez, Guillermo Sanchez-Delgado, Yolanda Garcia-Rivero, Juan M. A. Alcantara, Wendy D. Martinez-Avila, Maria V. Muñoz-Hernandez, Josune Olza, Mariëtte R. Boon, Patrick C. N. Rensen, Jose M. Llamas-Elvira, Jonatan R. Ruiz |
| Abstract |
Brown adipose tissue (BAT) activity is induced when humans are exposed to cold. Therefore, cold exposure prior to the (18)F-FDG-PET/CT scan is used as a tool to quantify BAT. Several cooling protocols, including fixed and personalized ones are currently in use. The aim of the present study was to determine the effect of a new personalized cooling protocol where the shivering threshold was measured on a separate day, on BAT volume and activity in young adults. A total of 47 adults (n = 28 women) aged 22 ± 2 years participated in the study. We determined participants' shivering threshold (visually and self-reported) using a water perfused cooling vest in an air-conditioned cold room. 48-72 h later, participants wore the cooling vest set at ~4°C above the shivering threshold for 60 min prior to injection of (18)F-FDG and ~5°C above the shivering threshold for ~60 min after injection, until PET/CT scan. We quantified BAT following BARCIST 1.0 recommendations. We identified 40 participants (85%, n = 25 women) as PET+ and 7 (n = 3 women) as PET-. The PET+ group presented significantly higher BAT volume and activity than PET- group (all P < 0.05). PET+ women had higher BAT mean activity than PET+ men (SUVmean: 5.0 ± 1.6 vs. 3.6 ± 0.9 g/ml respectively, P = 0.003), and there were no significant sex differences in BAT volume (P = 0.161). A total of 9 out of 47 participants did not shiver during the shivering threshold test. Our findings are similar to previous cold-stimulated human BAT studies; therefore, we conclude that our personalized cooling protocol is able to activate BAT in young adults. |
X Demographics
The data shown below were collected from the profiles of 18 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 10 | 56% |
| Grenada | 1 | 6% |
| Switzerland | 1 | 6% |
| Unknown | 6 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 11 | 61% |
| Scientists | 5 | 28% |
| Practitioners (doctors, other healthcare professionals) | 2 | 11% |
Mendeley readers
The data shown below were compiled from readership statistics for 59 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 59 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 18 | 31% |
| Researcher | 10 | 17% |
| Student > Master | 7 | 12% |
| Other | 6 | 10% |
| Student > Bachelor | 2 | 3% |
| Other | 8 | 14% |
| Unknown | 8 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 10 | 17% |
| Nursing and Health Professions | 9 | 15% |
| Medicine and Dentistry | 9 | 15% |
| Sports and Recreations | 7 | 12% |
| Engineering | 4 | 7% |
| Other | 10 | 17% |
| Unknown | 10 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 20. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 February 2018.
All research outputs
#1,577,736
of 23,007,053 outputs
Outputs from Frontiers in Physiology
#844
of 13,760 outputs
Outputs of similar age
#34,524
of 329,244 outputs
Outputs of similar age from Frontiers in Physiology
#34
of 347 outputs
Altmetric has tracked 23,007,053 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 13,760 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 329,244 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 347 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.