https://t.co/wgtlzmONv2 "At the same time, BRLF1 can favor directly or indirectly the transcription of other early viral promoters, including the EBV IE gene, BZLF1 (Z), that could have a role in increasing FAS too."
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https://t.co/wgtlzmONv2 "In particular, the transcription factor immediate-early (IE) protein BRLF1 (R) – an inductor of the lytic form of EBV infection – can activate FASN expression through a p38 stress MAPK-dependent mechanism."
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https://t.co/wgtlzmONv2 "an enzyme that plays a key role in the cell endogenous fatty acid synthesis (FAS) mediating the multiple condensation reaction between malonil-CoA and acetyl-CoA molecules which leads to the palmitate FAS."
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https://t.co/wgtlzmONv2 "One common lipid metabolism alteration in EBV infection is the increased expression of fatty acid synthase (FASN),"