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Analysis of CRISPR-Cas System in Streptococcus thermophilus and Its Application

Overview of attention for article published in Frontiers in Microbiology, February 2018
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Title
Analysis of CRISPR-Cas System in Streptococcus thermophilus and Its Application
Published in
Frontiers in Microbiology, February 2018
DOI 10.3389/fmicb.2018.00257
Pubmed ID
Authors

Mengyuan Hao, Yanhua Cui, Xiaojun Qu

Abstract

CRISPR-Cas (Clustered regularly interspaced short palindromic repeats-CRISPR associated proteins) loci, which provide a specific immunity against exogenous elements, are hypervariable among distinct prokaryotes. Based on previous researches, this review focuses on concluding systematical genome editing protocols inStreptococcus thermophilus.Firstly, its protocols and optimized conditions in gene editing are introduced. What's more, classification and diversity analyses ofS. thermophilusCRISPR-Cas benefit the further understanding of evolution relationship amongStreptococcus.Ability of its foreign segment integration and spacer source analyses also indicate a new direction of phage resistance. Above all, all of these point out its potential to be regarded as another model system other than type II CRISPR-Cas inStreptococcus pyogenes.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 95 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 95 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 25 26%
Student > Master 14 15%
Researcher 9 9%
Student > Ph. D. Student 7 7%
Student > Doctoral Student 3 3%
Other 7 7%
Unknown 30 32%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 28 29%
Agricultural and Biological Sciences 14 15%
Immunology and Microbiology 7 7%
Chemistry 2 2%
Pharmacology, Toxicology and Pharmaceutical Science 2 2%
Other 7 7%
Unknown 35 37%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 March 2018.
All research outputs
#17,929,042
of 23,020,670 outputs
Outputs from Frontiers in Microbiology
#17,424
of 25,142 outputs
Outputs of similar age
#240,512
of 331,051 outputs
Outputs of similar age from Frontiers in Microbiology
#447
of 588 outputs
Altmetric has tracked 23,020,670 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 25,142 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.3. This one is in the 22nd percentile – i.e., 22% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 331,051 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 588 others from the same source and published within six weeks on either side of this one. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.